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Recent Development on Importance of Heterocyclic Amides as Potential Bioactive Molecules: A Review

[ Vol. 15 , Issue. 3 ]

Author(s):

Samridhi Thakral and Vikramjeet Singh*   Pages 316 - 336 ( 21 )

Abstract:


Background: Heterocyclic compounds are an integral part of the chemical and life sciences and constitute a considerable quantum of the modern research that is being currently pursued throughout the world.

Methods: This review was prepared by collecting the available literature reports on various databases and an extract was prepared for each report after thorough study and compiling the recent literature reports on heterocyclic amides from 2007 to 2018.

Results: This review summarizes the bio-potential of heterocyclic amides as antimicrobial, anticancer, anti-tubercular and antimalarial agents which would be very promising in the field of medicinal chemistry.

Conclusion: A wide variety of heterocyclic amides have already been reported and some are currently being used as active medicaments for the treatment of disease. Still, the research groups are focusing on the development of newer heterocyclic amide derivatives with better efficacy, potency and lesser side effects. This area has got the tremendous potential to come up with new chemical entities of medicinal importance.

Keywords:

Heterocycles, bioactivity, antimicrobial, anticancer, anti-tubercular, antimalarial.

Affiliation:

Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar -125001, Haryana, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar -125001, Haryana

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