Kollur S. Prasad* and Shwetha U. Ramachandrappa Pages 201 - 209 ( 9 )
Background:The variety of biological applications of vanadium impressed researchers to develop vanadium based drugs. The most well-known fact of vanadium is that it is necessary for human beings as an insulin-enhancing agent and herein, we mainly provide an overview of vanadium-baseddrugs and their applications in the medicinal field for the treatment of diseases such as diabetes and cancer. The first part of this review is focused on mechanistic studies involved in the anti-diabetic activ-ity. The latter part explains the use of vanadium and its related coordination compounds in the treatment of cancer.Methods: This review is purely based on literature search available in the database. We focused on the reports available on the recent advancements in the vanadium chemistry and its biological properties, mainly anti-diabetic and anticancer activities of vanadium based compounds. Results: The study of clinical trials of vanadium and its drug molecules imposed more demand due totheir remarkable activity with less toxicity. Conclusion: A brief literature survey was made pertaining to the applications of vanadium com-pounds/complexes. Particularly, special attention was paid to explaining mechanistic studies of vana-dium based compounds in the treatment of diabetes and cancer.
anadium compounds, anti-diabetic activity, anti-cancer drugs, ammonium metavandate, sulfuric acid, smoke-stacks.
Department of Sciences, Amrita School of Arts and Sciences, Mysuru, Amrita Vishwa Vidyapeetham, Karnataka-570 026, Department of Chemistry, Bapuji Institute of Engineering and Technology, Davanagere - 577 004, Karna-taka