The Influence of Heating and Photosensitization on the Stability of Lutein- Loaded Lipid-Core Nanocapsules

Author(s):

Aelson A.S. Brum, Médelin M. da Silva, Priscilla P. dos Santos, Allana V.S. Brasil, Karina Paese, Silvia S. Guterres, Simone H. Flôres and Alessandro de O. Rios*   Pages 1340 - 1345 ( 6 )

Abstract:

Background: Despite lutein is unstable in light, heat, and oxygen, it is a good quencher of singlet oxygen. The present study evaluated the stability of lutein (92% of purity) in Lipid-core Nanocapsules (Lutein-LNC) prepared through interfacial deposition of preformed polymer, during photosensitization (5-25°C) and heating (70-90°C).

Methods: The Lutein-LNC was characterized and presented a polydispersity index of 0.11, an average diameter of 191 nm (dynamic light scattering), zeta potential of -9.14 mV and entrapment efficiency of 100%.

Results and Discussion: During photosensitization and heating, Lutein-LNC exhibited activation Energy (Ea) of 24.67 kcal/mol and 9.96 kcal/mol, respectively, and these values of Lutein-LNC were higher than free lutein values, reported in other studies for both experiments.

Conclusion: The results obtained in this study suggested that nanotechnology can improve the stability of lutein for future applications in the food industry.

Keywords:

Heating, lutein, photodegradation, sensitizer, stability, zeaxanthin.

Affiliation:

Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS, Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS, Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS, Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS, Programa de Pos-Graduacao em Ciencias Farmaceuticas, Faculdade de Farmacia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS, Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS, Instituto de Ciencia e Tecnologia de Alimentos, Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Goncalves, n. 9500, CEP 91501-970, Porto Alegre, RS

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