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A Review of Eugenol-based Nanomedicine: Recent Advancements

[ Vol. 17 , Issue. 3 ]

Author(s):

Mohammed A. Jahangir, Mohamad Taleuzzaman*, Sarwar Beg, Surajpal Verma, Sadaf J. Gilani and Perwaiz Alam   Pages 214 - 219 ( 6 )

Abstract:


Eugenol is a bioactive compound commonly found in many herbal plants. The different reported sources of eugenol are clove, cinnamon, holy basil, and pepper. Several therapeutic activities of eugenol like antioxidant, antimicrobial, anesthetic, anti-inflammatory, anti-carcinogenic, neuroprotective agent, anti-diabetic and anti-cancer activities have been reported. However, due to limited aqueous solubility, it has poor bioavailability. Its therapeutic potential can be enhanced by developing eugenol nano-formulations like liposome, nanoparticles, microemulsions and micelles. This article extensively reviews the chemical and pharmacological properties of eugenol and its nano-formulations along with their biological activities.

Keywords:

Eugenol, nano formulation, microemulsions, micelles, pharmacological properties, pharmacokinetics.

Affiliation:

Nibha Institute of Pharmaceutical Sciences, Rajgir, Nalanda, Bihar-803116, Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Maulana Azad University, Jodhpur, 342802, Rajasthan, School of Pharmaceutical Education & Research, Jamia Hamdard (Hamdard University), New Delhi, School of Pharmaceutical Sciences(SPS), Lovely Professional University(LPU), Jalandhar-Delhi G.T. Road, National Highway-1, Phagwara, Punjab, College of Basic Health Science, Princess Nourahbint Abdulrahman University, Riyadh, School of Pharmaceutical Education & Research, Jamia Hamdard (Hamdard University), New Delhi

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